Ddx3y^em2Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ddx3y^em2Osb
• Name: DEAD box helicase 3, Y-linked; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6323445
• Synonyms: X/Y^Ddx3y-em2
• Gene: Ddx3y Location: ChrY:1260771-1286629 bp, - strand Genetic Position: ChrY, cytoband p
• Alliance: Ddx3y^em2Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Two small indels were generated by CRISPR/Cas9 editing, 10-bp and 6-bp within exon 4, that resulted in a frame shift. (J:274336)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ddx3y Mutation: 33 strains or lines available

References

• Original: J:274336 Matsumura T, et al., An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility. J Reprod Dev. 2019 Apr 12;65(2):121-128
• All: 2 reference(s)