Ddx3x^em2Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ddx3x^em2Osb
• Name: DEAD box helicase 3, X-linked; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6323448
• Synonyms: X^Ddx3x-em2
• Gene: Ddx3x Location: ChrX:13147261-13160222 bp, + strand Genetic Position: ChrX, 8.17 cM
• Alliance: Ddx3x^em2Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:274336
• Parent Cell Line: EGR-G01 (ES Cell)
• Strain of Origin: (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mutagenesis introduced a 29-bp deletion in the gene. (J:274336)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx3x Mutation: 8 strains or lines available

References

• Original: J:274336 Matsumura T, et al., An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility. J Reprod Dev. 2019 Apr 12;65(2):121-128
• All: 1 reference(s)