H3f4^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: H3f4^em1Osb
• Name: H3.4 histone, cluster member; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6323659
• Synonyms: H3mmT^em1Osb, H3t^tm1Osb
• Gene: H3f4 Location: Chr11:58852537-58853099 bp, + strand Genetic Position: Chr11, 36.39 cM
• Alliance: H3f4^em1Osb page

Mutation origin

• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• A 16 bp deletion including the intiation ATG was generated by CRISPR/Cas9 mutagenesis. (J:258191)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H3f4 Mutation: 0 strains or lines available

References

• Original: J:258191 Ueda J, et al., Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis. Cell Rep. 2017 Jan 17;18(3):593-600
• All: 1 reference(s)