Fgf7^{tm1e.1(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Fgf7^{tm1e.1(EUCOMM)Hmgu}
• Name: fibroblast growth factor 7; targeted mutation 1e.1, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6324182
• Gene: Fgf7 Location: Chr2:125876578-125933105 bp, + strand Genetic Position: Chr2, 61.76 cM, cytoband F-G
• Alliance: Fgf7^{tm1e.1(EUCOMM)Hmgu} page
• IMPC: Fgf7 gene page

Mutation origin

• Mutant Cell Line: HEPD0617_5_F12
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Fgf7^{tm1e(EUCOMM)Hmgu} allele resulted in the removal of the promoter-driven neomycin selection cassette leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:157065)

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf7 Mutation: 17 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 4 reference(s)