Nabp2tm1b(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Nabp2tm1b(KOMP)Wtsi |
Name: |
nucleic acid binding protein 2; targeted mutation 1b, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:6324183 |
Gene: |
Nabp2 Location: Chr10:128237264-128247361 bp, - strand Genetic Position: Chr10, 76.55 cM, cytoband D3
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Alliance: |
Nabp2tm1b(KOMP)Wtsi page
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IMPC: |
Nabp2 gene page |
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Mutant Cell Line: |
EPD0256_1_D05 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A1.N3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Pgk_P
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Mutation details: The L1L2_Pgk_P cassette was inserted at position 128243765 of Chromosome 10 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the PGK promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 128245020. The critical exon(s) is/are thus flanked by loxP sites. A null/knockout allele was created by cre recombinase expression in mice carrying the tm1a allele to remove the neo selection cassette and loxP-flanked critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:148605)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nabp2 Mutation: |
16 strains or lines available
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Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
4 reference(s) |
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