Gata5^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Gata5^{tm1.1(KOMP)Vlcg}
• Name: GATA binding protein 5; targeted mutation 1.1, Velocigene
• MGI ID: MGI:6324184
• Synonyms: Gata5^{tm1b(KOMP)Wtsi}
• Gene: Gata5 Location: Chr2:179966926-179976492 bp, - strand Genetic Position: Chr2, 102.85 cM
• Alliance: Gata5^{tm1.1(KOMP)Vlcg} page
• IMPC: Gata5 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7569bp between positions 180061503-180069071 of Chromosome 2 (Genome Build37). The loxP-flanked neomycin selection cassette was removed, leaving a beta-galactosidase gene which replaced the coding exon. (J:136110)

Expression

In Mice Carrying this Mutation:

46 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gata5 Mutation: 17 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)