Ube2d1tm3e(EUCOMM)Wtsi
Targeted Allele Detail
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Symbol: |
Ube2d1tm3e(EUCOMM)Wtsi |
Name: |
ubiquitin-conjugating enzyme E2D 1; targeted mutation 3e, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:6324191 |
Gene: |
Ube2d1 Location: Chr10:71090810-71121048 bp, - strand Genetic Position: Chr10, 36.85 cM
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Alliance: |
Ube2d1tm3e(EUCOMM)Wtsi page
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IMPC: |
Ube2d1 gene page |
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Mutant Cell Line: |
MEPD1008_4_C01 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3.N1.C2 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Conditional ready, Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Pgk_P cassette was inserted at position 71096138 of Chromosome 10 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the PGK promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:155845)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
All: |
4 reference(s) |
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