Pirt^{tm3.1(cre)Xzd}
Targeted Allele Detail

Summary

• Symbol: Pirt^{tm3.1(cre)Xzd}
• Name: phosphoinositide-interacting regulator of transient receptor potential channels; targeted mutation 3.1, Xinzhong Dong
• MGI ID: MGI:6332952
• Synonyms: Pirt-cre
• Gene: Pirt Location: Chr11:66802807-66820702 bp, + strand Genetic Position: Chr11, 40.59 cM
• Alliance: Pirt^{tm3.1(cre)Xzd} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Recombinase)
• Mutation: Insertion
• Pirt^{tm3.1(cre)Xzd} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pirt (MGI:2443635)

• Mutation details: Cre expression cassette replaced the entire ORF of the Pirt gene to be under the control of Pirt regulation. The neo-selection cassette was removed. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pirt (mouse) Summary of all recombinase alleles driven by Pirt. Alliance mouse Pirt gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pirt Mutation: 13 strains or lines available

References

• Original: J:247573 Kim YS, et al., Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain. Neuron. 2016 Sep 07;91(5):1085-1096
• All: 23 reference(s)