Erp29^tm1Dfer
Targeted Allele Detail

Summary

• Symbol: Erp29^tm1Dfer
• Name: endoplasmic reticulum protein 29; targeted mutation 1, David Ferrari
• MGI ID: MGI:6342880
• Gene: Erp29 Location: Chr5:121582816-121590537 bp, - strand Genetic Position: Chr5, 61.8 cM, cytoband F
• Alliance: Erp29^tm1Dfer page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217253
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ gene was inserted in frame at the intiation codon, followed by a loxP-flanked neomycin selection cassette. (J:277661)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Erp29 Mutation: 33 strains or lines available

References

• Original: J:217253 Hirsch I, et al., ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6-CHOP pathway of stress response. Apoptosis. 2014 May;19(5):801-15
• All: 2 reference(s)