Megf6^em3(cre)Zzhg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Megf6^em3(cre)Zzhg
• Name: multiple EGF-like-domains 6; endonuclease-mediated mutation 3, Zhen Zhang
• MGI ID: MGI:6343189
• Synonyms: Megf6^Cre
• Gene: Megf6 Location: Chr4:154255187-154360170 bp, + strand Genetic Position: Chr4, 83.89 cM
• Alliance: Megf6^em3(cre)Zzhg page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Megf6^em3(cre)Zzhg expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Megf6 (MGI:1919351)

• Mutation details: CRISPR-targeting with a donor plasmid introduced a cre recombinase gene downstream of the ATG translation start site. (J:271659)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Megf6 (mouse) Summary of all recombinase alleles driven by Megf6. Comparative matrix view of recombinase activities Alliance mouse Megf6 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Megf6 Mutation: 70 strains or lines available

References

• Original: J:271659 Wang Y, et al., Generation and characterization of Megf6 null and Cre knock-in alleles. Genesis. 2019 Feb;57(2):e23262
• All: 1 reference(s)