Ankrd31^em2Atot
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ankrd31^em2Atot
• Name: ankyrin repeat domain 31; endonuclease-mediated mutation 2, Attila Toth
• MGI ID: MGI:6343193
• Synonyms: Ankrd31^mut2, mut2
• Gene: Ankrd31 Location: Chr13:96884797-97046302 bp, + strand Genetic Position: Chr13, Syntenic
• Alliance: Ankrd31^em2Atot page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRIPSR/Cas9 genome editing created a deleion of the 3' end of exon 6 and part of intron 6. This mutation is predicted to result in a frameshift in the encoded protein. (J:276412)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ankrd31 Mutation: 39 strains or lines available

References

• Original: J:276412 Papanikos F, et al., Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes. Mol Cell. 2019 Jun 6;74(5):1069-1085.e11
• All: 2 reference(s)