Tg(CAG-C1qtnf6)#Yiw
Transgene Detail

Summary

• Symbol: Tg(CAG-C1qtnf6)#Yiw
• Name: transgene insertion, Yoichiro Iwakura
• MGI ID: MGI:6343247
• Transgene: Tg(CAG-C1qtnf6)#Yiw Location: unknown
• Alliance: Tg(CAG-C1qtnf6)#Yiw page

Transgene origin

• Strain of Origin: C57BL/6JJcl

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-C1qtnf6)#Yiw expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ifnb1 (MGI:107657)

• Mutation details: A full-length mouse C1qtnf6 complementary DNA is expressed under the control of the CAG promoter which is composed of the cytomegalovirus (CMV) immediate-early enhancer, chicken beta-actin promoter, and chicken beta-actin intron. The pound symbol is used when no line is specified and/or lines are pooled. Serum CTRP6 levels are ~2.5 times higher in transgenic mice than in non-transgenic littermates. (J:227217)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:227217 Murayama MA, et al., CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun. 2015;6:8483
• All: 1 reference(s)