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Fbxw11tm2Nakay
Targeted Allele Detail
Summary
Symbol: Fbxw11tm2Nakay
Name: F-box and WD-40 domain protein 11; targeted mutation 2, Keiko Nakayama
MGI ID: MGI:6343252
Synonyms: beta-TrCP2F
Gene: Fbxw11  Location: Chr11:32592724-32696816 bp, + strand  Genetic Position: Chr11, 19.02 cM
Alliance: Fbxw11tm2Nakay page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:228222
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exon 5 was flanked by loxP sequences. (J:228222)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fbxw11 Mutation:  72 strains or lines available
References
Original:  J:228222 Nakagawa T, et al., S6 Kinase- and beta-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation. Mol Cell Biol. 2015 Oct;35(20):3517-27
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory