Nup88^em1Jvd
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nup88^em1Jvd
• Name: nucleoporin 88; endonuclease-mediated mutation 1, Jan MA van Deursen
• MGI ID: MGI:6343328
• Gene: Nup88 Location: Chr11:70833884-70860799 bp, - strand Genetic Position: Chr11, 43.21 cM
• Alliance: Nup88^em1Jvd page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN mutagenesis induced an 11-bp frame-shift deletion. (J:231166)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nup88 Mutation: 44 strains or lines available

References

• Original: J:231166 Naylor RM, et al., Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy. J Clin Invest. 2016 Feb 1;126(2):543-59
• All: 1 reference(s)