Cracr2a^tm1.1Ygwa
Targeted Allele Detail

Summary

• Symbol: Cracr2a^tm1.1Ygwa
• Name: calcium release activated channel regulator 2A; targeted mutation 1.1, Yousang Gwack
• MGI ID: MGI:6343391
• Synonyms: CRACR2A^fl
• Gene: Cracr2a Location: Chr6:127538299-127651197 bp, + strand Genetic Position: Chr6, 62.39 cM
• Alliance: Cracr2a^tm1.1Ygwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259523
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 3 and 4 are flanked by loxP sites. (J:259523)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cracr2a Mutation: 25 strains or lines available

References

• Original: J:259523 Srikanth S, et al., A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals. Sci Signal. 2016 Mar 22;9(420):ra31
• All: 2 reference(s)