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Nlrp2tm1.2Itl
Targeted Allele Detail
Summary
Symbol: Nlrp2tm1.2Itl
Name: NLR family, pyrin domain containing 2; targeted mutation 1.2, Ingenious Targeting Laboratory
MGI ID: MGI:6343489
Synonyms: Nlrp2-
Gene: Nlrp2  Location: Chr7:5301546-5354034 bp, - strand  Genetic Position: Chr7, 3.07 cM, cytoband A1
Alliance: Nlrp2tm1.2Itl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:237496
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 5 is deleted following cre-mediated recombination of flanking loxP sites. (J:237496)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nlrp2 Mutation:  74 strains or lines available
References
Original:  J:237496 Kuchmiy AA, et al., NLRP2 controls age-associated maternal fertility. J Exp Med. 2016 Dec 12;213(13):2851-2860
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory