Tctn3^tm1.2Blnw
Targeted Allele Detail

Summary

• Symbol: Tctn3^tm1.2Blnw
• Name: tectonic family member 3; targeted mutation 1.2, Baolin Wang
• MGI ID: MGI:6343517
• Gene: Tctn3 Location: Chr19:40584890-40600677 bp, - strand Genetic Position: Chr19, 34.25 cM
• Alliance: Tctn3^tm1.2Blnw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:249241
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 3 was deleted following Cre-mediated recombination of flanking loxP sites in the germline. (J:249241)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tctn3 Mutation: 19 strains or lines available

References

• Original: J:249241 Wang C, et al., Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse. Dev Biol. 2017 Oct 1;430(1):156-165
• All: 1 reference(s)