Baiap2l1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Baiap2l1^tm1.1Arte
• Name: BAI1-associated protein 2-like 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6355370
• Synonyms: IRTKS^-
• Gene: Baiap2l1 Location: Chr5:144201336-144294922 bp, - strand Genetic Position: Chr5, 83.24 cM
• Alliance: Baiap2l1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:275147
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site followed by FRT-flanked Neo cassette was inserted into intron 1 and an F3-flanked Puro cassette followed by a second loxP site was inserted into intron 2. Cre-mediated recombination removed exons 2 as well as the neomycin and puromycin cassettes. The null allele results in splicing of exon 1 to exon 3, which is expected to create a premature stop codon in exon 3 and give a 18-amino acid truncated product that lacks all functional domains. (J:275147)

Expression

In Mice Carrying this Mutation:

96 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Baiap2l1 Mutation: 46 strains or lines available

References

• Original: J:275147 Chou AM, et al., Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development. Sci Rep. 2017 Jan 9;7:40485
• All: 1 reference(s)