Utp25^em2Glo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Utp25^em2Glo
• Name: UTP25 small subunit processome component; endonuclease-mediated mutation 2, Guillermina Lozano
• MGI ID: MGI:6355371
• Synonyms: Diexf^13ins
• Gene: Utp25 Location: Chr1:192786707-192812603 bp, - strand Genetic Position: Chr1, 97.56 cM
• Alliance: Utp25^em2Glo page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: The molecular lesion is a 13 base pair insertion in exon 1 resulting in a frame shift and the introduction of a premature stop codon. The encoded protein is predicted to terminate after 28 amino acids (26 endogenous and 2 novel amino acids). (J:272648)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Utp25 Mutation: 47 strains or lines available

References

• Original: J:272648 Aryal NK, et al., Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53. Oncotarget. 2017 Nov 28;8(61):103996-104006
• All: 1 reference(s)