Idh3b^em1Jkn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Idh3b^em1Jkn
• Name: isocitrate dehydrogenase 3 (NAD+) beta; endonuclease-mediated mutation 1, Ian J Jackson
• MGI ID: MGI:6355403
• Gene: Idh3b Location: Chr2:130121229-130126371 bp, - strand Genetic Position: Chr2, 63.2 cM, cytoband F3
• Alliance: Idh3b^em1Jkn page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• The molecular lesion is an 8bp deletion mutation, c.478_487delCCAATGGA. (J:267900)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Idh3b Mutation: 26 strains or lines available

References

• Original: J:267900 Findlay AS, et al., Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function. Dis Model Mech. 2018 Dec 18;11(12):dmm036426
• All: 1 reference(s)