Tardbp^Rgsc2268
Chemically induced Allele Detail

Summary

• Symbol: Tardbp^Rgsc2268
• Name: TAR DNA binding protein; Riken Genomic Sciences Center 2268
• MGI ID: MGI:6355454
• Synonyms: F210I, GD000108, RRM2mut
• Gene: Tardbp Location: Chr4:148696839-148711476 bp, - strand Genetic Position: Chr4, 78.77 cM
• Alliance: Tardbp^Rgsc2268 page

Mutation origin

• Strain of Origin: C57BL/6JJcl

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph, Modified isoform(s))
• Mutation: Single point mutation
• Mutation details: The ENU-induced mutation is a c.628T>A substitution that changes phenylalanine codon 210 to an isoleucine codon (p.Phe210Ile, p.F210I). The mutation is located in the second RNA recognition motif (RRM2) domain of the encoded peptide. (J:101000)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any Tardbp Mutation: 68 strains or lines available

References

• Original: J:101000 Sakuraba Y, et al., Molecular characterization of ENU mouse mutagenesis and archives. Biochem Biophys Res Commun. 2005 Oct 21;336(2):609-16
• All: 3 reference(s)