Shisa6^em1Syos
Endonuclease-mediated Allele Detail

Summary

• Symbol: Shisa6^em1Syos
• Name: shisa family member 6; endonuclease-mediated mutation 1, Shosei Yoshida
• MGI ID: MGI:6355919
• Synonyms: Shisa6⁶⁺⁵⁰², Shisa6^delta6+502, Shisa6^KO
• Gene: Shisa6 Location: Chr11:66102551-66416790 bp, - strand Genetic Position: Chr11, 40.55 cM
• Alliance: Shisa6^em1Syos page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The molecular lesion is an in-frame stop codon as a result of a 6-bp deletion and a 502-bp insertion. (J:257319)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shisa6 Mutation: 15 strains or lines available

References

• Original: J:257319 Tokue M, et al., SHISA6 Confers Resistance to Differentiation-Promoting Wnt/beta-Catenin Signaling in Mouse Spermatogenic Stem Cells. Stem Cell Reports. 2017 Mar 14;8(3):561-575
• All: 1 reference(s)