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Sec31aem3(IMPC)H
Endonuclease-mediated Allele Detail
Summary
Symbol: Sec31aem3(IMPC)H
Name: SEC31 homolog A, COPII coat complex component; endonuclease-mediated mutation 3, Harwell
MGI ID: MGI:6355926
Gene: Sec31a  Location: Chr5:100509508-100564093 bp, - strand  Genetic Position: Chr5, 48.48 cM, cytoband E3
Alliance: Sec31aem3(IMPC)H page
IMPC: Sec31a gene page
Mutation
origin
Strain of Origin:  C57BL/6NTac
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA and 4 guide sequences CCAAACTGACTGTAGTGAATGGC, CTAGAAACTGAACACTCTAAGGG, GAACGTTCTGAGTGATCGAAAGG, AACACTCTAAGGGAGCCCCCTGG, which resulted in a Exon Deletion. (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sec31a Mutation:  70 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory