Tafa2^tm1Zgwg
Targeted Allele Detail

Summary

• Symbol: Tafa2^tm1Zgwg
• Name: TAFA chemokine like family member 2; targeted mutation 1, Zhugang Wang
• MGI ID: MGI:6355950
• Synonyms: Tafa-2^-
• Gene: Tafa2 Location: Chr10:123099901-123577109 bp, + strand Genetic Position: Chr10, 72.31 cM
• Alliance: Tafa2^tm1Zgwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271697
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 2172-bp genomic fragment containing exons 6 and 7, which are common for all gene transcripts, was replaced with a neomycin selection cassette. (J:271697)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tafa2 Mutation: 18 strains or lines available

References

• Original: J:271697 Wang X, et al., Tafa-2 plays an essential role in neuronal survival and neurobiological function in mice. Acta Biochim Biophys Sin (Shanghai). 2018 Oct 1;50(10):984-995
• All: 1 reference(s)