Rubcnl^em1Qsun
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rubcnl^em1Qsun
• Name: RUN and cysteine rich domain containing beclin 1 interacting protein like; endonuclease-mediated mutation 1, Qiming Sun
• MGI ID: MGI:6356294
• Synonyms: Pacer^f
• Gene: Rubcnl Location: Chr14:75253467-75289972 bp, + strand Genetic Position: Chr14, 39.53 cM
• Alliance: Rubcnl^em1Qsun page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology was used to flank exon 3 of the mouse gene with loxP sites. (J:272052)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rubcnl Mutation: 47 strains or lines available

References

• Original: J:272052 Cheng X, et al., Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism. Mol Cell. 2019 Feb 21;73(4):788-802.e7
• All: 1 reference(s)