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Efcab9em2Chng
Endonuclease-mediated Allele Detail
Summary
Symbol: Efcab9em2Chng
Name: EF-hand calcium binding domain 9; endonuclease-mediated mutation 2, Jean-Ju Chung
MGI ID: MGI:6356321
Synonyms: Mut (5del)
Gene: Efcab9  Location: Chr11:32472751-32482081 bp, - strand  Genetic Position: Chr11, 18.97 cM, cytoband A5
Alliance: Efcab9em2Chng page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 mutagenesis induced a 5 bp deletion in exon 1. This results in a frameshift and early termination of translation. (J:276402)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Efcab9 Mutation:  12 strains or lines available
References
Original:  J:276402 Hwang JY, et al., Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility. Cell. 2019 May 30;177(6):1480-1494.e19
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory