Zcchc3^em1Hbsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zcchc3^em1Hbsh
• Name: zinc finger, CCHC domain containing 3; endonuclease-mediated mutation 1, H-B Shu
• MGI ID: MGI:6356330
• Synonyms: Zcchc3^-
• Gene: Zcchc3 Location: Chr2:152253875-152256711 bp, - strand Genetic Position: Chr2, 74.98 cM
• Alliance: Zcchc3^em1Hbsh page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• A knockout mutation was generated by CRISPR/Cas9 mutagenesis. Details not provided. (J:271802)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zcchc3 Mutation: 11 strains or lines available

References

• Original: J:268028 Lian H, et al., The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors. Immunity. 2018 Sep 18;49(3):438-448.e5
• All: 3 reference(s)