Slc2a6^em1Kusu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc2a6^em1Kusu
• Name: solute carrier family 2 (facilitated glucose transporter), member 6; endonuclease-mediated mutation 1, Hiroyuki Kusuhara
• MGI ID: MGI:6356342
• Synonyms: line 16 (L16)
• Gene: Slc2a6 Location: Chr2:26911375-26918010 bp, - strand Genetic Position: Chr2, 19.18 cM
• Alliance: Slc2a6^em1Kusu page

Mutation origin

• Strain of Origin: C57BL/6JCrlj

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mutagenesis induced a 10 bp deletion in exon 3. (J:270487)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc2a6 Mutation: 19 strains or lines available

References

• Original: J:270487 Maedera S, et al., GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates glycolysis in macrophages. FEBS Lett. 2019 Jan;593(2):195-208
• All: 1 reference(s)