Stra8^{em1(GFP/cre)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stra8^{em1(GFP/cre)Smoc}
• Name: stimulated by retinoic acid gene 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6356355
• Synonyms: Stra8-Cre, Stra8-GFPCre
• Gene: Stra8 Location: Chr6:34897098-34916279 bp, + strand Genetic Position: Chr6, 15.2 cM
• Alliance: Stra8^{em1(GFP/cre)Smoc} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase, Reporter)
• Mutation: Insertion
• Stra8^{em1(GFP/cre)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Stra8 (MGI:107917)

• Mutation details: A cDNA encoding the GFPCre fusion protein was inserted into the last coding exon of Stra8, and a 2A peptide sequence was included to link Stra8 and GFPCre to allow expression of both genes. (J:250428)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Stra8 (mouse) Summary of all recombinase alleles driven by Stra8. Alliance mouse Stra8 gene page

Expression

In Mice Carrying this Mutation:

55 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stra8 Mutation: 36 strains or lines available

References

• Original: J:250428 Lin Z, et al., Mettl3-/Mettl14-mediated mRNA N(6)-methyladenosine modulates murine spermatogenesis. Cell Res. 2017 Oct;27(10):1216-1230
• All: 19 reference(s)