Stk38^em1Flca
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stk38^em1Flca
• Name: serine/threonine kinase 38; endonuclease-mediated mutation 1, Francis C Luca
• MGI ID: MGI:6356402
• Synonyms: Ndr1^delta4, Stk38^delta4
• Gene: Stk38 Location: Chr17:29189854-29226969 bp, - strand Genetic Position: Chr17, 15.03 cM
• Alliance: Stk38^em1Flca page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: CRISPR targeting of exon 4 resulted in a frame shift mutation (CTC to AGCG) and premature termination of the trasncript in exon 4. (J:265036)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk38 Mutation: 55 strains or lines available

References

• Original: J:265036 Leger H, et al., Ndr kinases regulate retinal interneuron proliferation and homeostasis. Sci Rep. 2018 Aug 22;8(1):12544
• All: 1 reference(s)