Zfp131^tm1.1Mytk
Targeted Allele Detail

Summary

• Symbol: Zfp131^tm1.1Mytk
• Name: zinc finger protein 131; targeted mutation 1.1, Shoichiro Miyatake
• MGI ID: MGI:6356577
• Synonyms: Znf131 floxed
• Gene: Zfp131 Location: Chr13:120226723-120252425 bp, - strand Genetic Position: Chr13, Syntenic
• Alliance: Zfp131^tm1.1Mytk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271921
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 4 encoding a part of the BTB domain of the gene was flanked with loxP sites. Chimeric males carrying targeted allele were bred to transgenic FLPe driven by human Actb promoter to delete neomycin resistance cassette and to obtain mice carrying the floxed allele. (J:271921)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp131 Mutation: 24 strains or lines available

References

• Original: J:271921 Iguchi T, et al., BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells. J Immunol. 2015 Aug 1;195(3):982-93
• All: 2 reference(s)