Kirrel2^tm1.1Tbh
Targeted Allele Detail

Summary

• Symbol: Kirrel2^tm1.1Tbh
• Name: kirre like nephrin family adhesion molecule 2; targeted mutation 1.1, Tobias B Huber
• MGI ID: MGI:6356799
• Synonyms: Neph3 KO
• Gene: Kirrel2 Location: Chr7:30146959-30157115 bp, - strand Genetic Position: Chr7, 18.36 cM
• Alliance: Kirrel2^tm1.1Tbh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241326
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LoxP sites were inserted into exon 1 upstream of the start codon and into the intronic sequence between exon 2 and exon 3. Cre mediated recombination in the germline resulted in the deletion of the loxP-flanked sequences. (J:241326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kirrel2 Mutation: 25 strains or lines available

References

• Original: J:241326 Grahammer F, et al., A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight. 2016 Jun 16;1(9)
• All: 1 reference(s)