Slc15a4^tm1Tkyo
Targeted Allele Detail

Summary

• Symbol: Slc15a4^tm1Tkyo
• Name: solute carrier family 15, member 4; targeted mutation 1, Norihiro Kato
• MGI ID: MGI:6356820
• Synonyms: Pht1^-, SLC15A4^-
• Gene: Slc15a4 Location: Chr5:127672728-127709961 bp, - strand Genetic Position: Chr5, 66.0 cM
• Alliance: Slc15a4^tm1Tkyo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:270965
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 2-5 of the gene. (J:270965)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc15a4 Mutation: 43 strains or lines available

References

• Original: J:270965 Sasawatari S, et al., The solute carrier family 15A4 regulates TLR9 and NOD1 functions in the innate immune system and promotes colitis in mice. Gastroenterology. 2011 May;140(5):1513-25
• All: 6 reference(s)