Amotl1^tm1Laho
Targeted Allele Detail

Summary

• Symbol: Amotl1^tm1Laho
• Name: angiomotin-like 1; targeted mutation 1, Lars Holmgren
• MGI ID: MGI:6356823
• Synonyms: amotL1^flox
• Gene: Amotl1 Location: Chr9:14453262-14556352 bp, - strand Genetic Position: Chr9, 4.12 cM, cytoband A3
• Alliance: Amotl1^tm1Laho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253854
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 5 and 6 are flanked with loxP sites and an frt-flanked neomycin selection cassette. Deletion of the loxP flanked exons will result in a frameshift and premature stop codon at position 300. (J:253854)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Amotl1 Mutation: 56 strains or lines available

References

• Original: J:253854 Zheng Y, et al., Angiomotin like-1 is a novel component of the N-cadherin complex affecting endothelial/pericyte interaction in normal and tumor angiogenesis. Sci Rep. 2016 Jul 28;6:30622
• All: 1 reference(s)