Mir199a-2^tm1Kinn
Targeted Allele Detail

Summary

• Symbol: Mir199a-2^tm1Kinn
• Name: microRNA 199a-2; targeted mutation 1, Kinichi Nakashima
• MGI ID: MGI:6357166
• Synonyms: mIR-199a-2 KO
• Gene: Mir199a-2 Location: Chr1:162045383-162045492 bp, + strand Genetic Position: Chr1, 70.06 cM
• Alliance: Mir199a-2^tm1Kinn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256665
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The entire coding sequence was replaced with a loxP-flanked neomycin selection cassette. (J:256665)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir199a-2 Mutation: 0 strains or lines available

References

• Original: J:256665 Tsujimura K, et al., miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes. Cell Rep. 2015 Sep 22;12(11):1887-901
• All: 2 reference(s)