Slfn5^tm1Aki
Targeted Allele Detail

Summary

• Symbol: Slfn5^tm1Aki
• Name: schlafen 5; targeted mutation 1, Shizuo Akira
• MGI ID: MGI:6357190
• Synonyms: Slfn5^-
• Gene: Slfn5 Location: Chr11:82842175-82855666 bp, + strand Genetic Position: Chr11, 50.3 cM
• Alliance: Slfn5^tm1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258797
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Molecular details were not provided. (J:258797)

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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hm1	Slfn5^tm1Aki/Slfn5^tm1Aki	Not Specified

Phenotypes:

Affected Systems	hm1
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immune system	N
immune system phenotype	N

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slfn5 Mutation: 43 strains or lines available

References

• Original: J:258797 Nakagawa K, et al., Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis. Int Immunol. 2018 Mar 8;30(2):69-78
• All: 1 reference(s)