Arhgap36^em1Seul
Endonuclease-mediated Allele Detail

Summary

• Symbol: Arhgap36^em1Seul
• Name: Rho GTPase activating protein 36; endonuclease-mediated mutation 1, Seunghee Lee
• MGI ID: MGI:6357898
• Synonyms: Arhgap36^-
• Gene: Arhgap36 Location: ChrX:48552822-48589121 bp, + strand Genetic Position: ChrX, 25.95 cM
• Alliance: Arhgap36^em1Seul page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2 was targeted by an sgRNA (5'-GACTGCTTACCACGAACTCGTGG-3') using CRISPR/Cas9 technology. The resulting 7 bp deletion (CTCGTGG) created a knockout allele. (J:277700)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgap36 Mutation: 4 strains or lines available

References

• Original: J:277700 Nam H, et al., Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification. Elife. 2019 Jul 15;8:e46683
• All: 1 reference(s)