Rgs21^tm1.2Dski
Targeted Allele Detail

Summary

• Symbol: Rgs21^tm1.2Dski
• Name: regulator of G-protein signalling 21; targeted mutation 1.2, David Siderovski
• MGI ID: MGI:6357987
• Synonyms: Rgs21^delta5, Rgs21^tm1.2Geno
• Gene: Rgs21 Location: Chr1:144392388-144443185 bp, - strand Genetic Position: Chr1, 62.66 cM
• Alliance: Rgs21^tm1.2Dski page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278472
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 5 was deleted via Cre-mediated recombination of flanking loxP sites. (J:278472)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgs21 Mutation: 11 strains or lines available

References

• Original: J:278472 Schroer AB, et al., Development of Full Sweet, Umami, and Bitter Taste Responsiveness Requires Regulator of G protein Signaling-21 (RGS21). Chem Senses. 2018 May 23;43(5):367-378
• All: 1 reference(s)