Mia2^tm1.1Zhxu
Targeted Allele Detail

Summary

• Symbol: Mia2^tm1.1Zhxu
• Name: MIA SH3 domain ER export factor 2; targeted mutation 1.1, Zhiheng Xu
• MGI ID: MGI:6358034
• Synonyms: Mea6^delta
• Gene: Mia2 Location: Chr12:59142368-59237006 bp, + strand Genetic Position: Chr12, 26.0 cM
• Alliance: Mia2^tm1.1Zhxu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:268333
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 11 was flanked by loxP sites and an FRT-flanked neomycin cassette was inserted in intron 11 before the second loxP site. Cre-mediated recombination removed exon 11 and the neomycin cassette. (J:268333)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mia2 Mutation: 31 strains or lines available

References

• Original: J:268333 Wang Y, et al., Mea6 controls VLDL transport through the coordinated regulation of COPII assembly. Cell Res. 2016 Jul;26(7):787-804
• All: 2 reference(s)