Tg(Zic4-icre/ERT2)1Kess
Transgene Detail

Summary

• Symbol: Tg(Zic4-icre/ERT2)1Kess
• Name: transgene insertion 1, Nicoletta Kessaris
• MGI ID: MGI:6358140
• Synonyms: Zic4-CreER^T2
• Transgene: Tg(Zic4-icre/ERT2)1Kess Location: unknown
• Alliance: Tg(Zic4-icre/ERT2)1Kess page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Zic4-icre/ERT2)1Kess expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Zic4 (MGI:107201)

• Mutation details: Insertion of iCreERT2-polyA construct into the Zic4 gene of a mouse BAC clone with an Frt-flanked kanamycin selection cassette. The selection cassette was removed from the construct before injection inot fertilized eggs. Inducible cre is expressed under the control of the Zic4 promoter. (J:254523)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Zic4 (mouse) Summary of all recombinase alleles driven by Zic4. Alliance mouse Zic4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:254523 Magno L, et al., NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory. Cell Rep. 2017 Aug 15;20(7):1572-1584
• All: 1 reference(s)