Ifi204^tm1.1Cjul
Targeted Allele Detail

Summary

• Symbol: Ifi204^tm1.1Cjul
• Name: interferon activated gene 204; targeted mutation 1.1, Chuan-ju Liu
• MGI ID: MGI:6358241
• Synonyms: p204^-
• Gene: Ifi204 Location: Chr1:173574859-173594509 bp, - strand Genetic Position: Chr1, 80.63 cM
• Alliance: Ifi204^tm1.1Cjul page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:270123
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 to 5 were flanked by loxP sites. Cre-mediated recombination removed the floxed region. Western blot analysis confirmed absence of protein expression in bone marrow derived macrophages and embryonic fibroblasts. (J:270123)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifi204 Mutation: 47 strains or lines available

References

• Original: J:270123 Yi YS, et al., p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice. EBioMedicine. 2018 Mar;29:78-91
• All: 2 reference(s)