Commd3^tm1.1Ksuz
Targeted Allele Detail

Summary

• Symbol: Commd3^tm1.1Ksuz
• Name: COMM domain containing 3; targeted mutation 1.1, Kazuhiro Suzuki
• MGI ID: MGI:6358284
• Synonyms: Commd3^f
• Gene: Commd3 Location: Chr2:18677246-18681042 bp, + strand Genetic Position: Chr2, 12.9 cM
• Alliance: Commd3^tm1.1Ksuz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278399
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The PG00187_Z_7_H01 targeting vector flanked exons 2 through 7 with loxP sites. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:278399)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Commd3 Mutation: 15 strains or lines available

References

• Original: J:278399 Nakai A, et al., The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors. J Exp Med. 2019 Jul 1;216(7):1630-1647
• All: 2 reference(s)