Tg(Tie1-RHOA*T19N)#Jiao
Transgene Detail

Summary

• Symbol: Tg(Tie1-RHOA*T19N)#Jiao
• Name: transgene insertion, Kai Jiao
• MGI ID: MGI:6358307
• Transgene: Tg(Tie1-RHOA*T19N)#Jiao Location: unknown
• Alliance: Tg(Tie1-RHOA*T19N)#Jiao page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Dominant negative, Epitope tag, Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tie1-RHOA*T19N)#Jiao expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  RHOA (387)

  Rhoa	(MGI:1096342)

  Expresses a dominant negative

• Mutation details: A Myc-tagged dominant negative human RHOA gene with the T19N mutation is driven by the approximate 1 kb mouse Tie1 promoter. (J:254695)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:254695 Peng Y, et al., Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice. Cardiovasc Res. 2016 Nov 1;112(2):532-542
• All: 1 reference(s)