Mir205^em1Oers
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir205^em1Oers
• Name: microRNA 205; endonuclease-mediated mutation 1, Nicolai S van Oers
• MGI ID: MGI:6358377
• Synonyms: miR-205^KI
• Gene: Mir205 Location: Chr1:193189771-193189838 bp, - strand Genetic Position: Chr1, 97.82 cM
• Alliance: Mir205^em1Oers page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting of the nggg site introduced a 10 bp nucleotide substitution (NR_029592.1:r.9_30delinsugggggguuccagcgaauucgg). (J:278363)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir205 Mutation: 3 strains or lines available

References

• Original: J:278363 Du Q, et al., MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary. Dev Cell. 2019 May 20;49(4):618-631.e5
• All: 1 reference(s)