Bcl2l11^em1Flv
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bcl2l11^em1Flv
• Name: BCL2 like 11; endonuclease-mediated mutation 1, Richard A Flavell
• MGI ID: MGI:6358427
• Gene: Bcl2l11 Location: Chr2:127967958-128004467 bp, + strand Genetic Position: Chr2, 62.23 cM, cytoband F3-G1
• Alliance: Bcl2l11^em1Flv page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed the first coding exon. (J:236609)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl2l11 Mutation: 36 strains or lines available

Notes

Generated in zygotes with Morrbid^em1Flv.

References

• Original: J:236609 Kotzin JJ, et al., The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Nature. 2016 Aug 15;537(7619):239-243
• All: 1 reference(s)