Zcwpw1^em1Kliu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zcwpw1^em1Kliu
• Name: zinc finger, CW type with PWWP domain 1; endonuclease-mediated mutation 1, Kui Lui
• MGI ID: MGI:6358521
• Gene: Zcwpw1 Location: Chr5:137786060-137820883 bp, + strand Genetic Position: Chr5, 76.71 cM
• Alliance: Zcwpw1^em1Kliu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed 4 kb spanning exons 4 through 7. (J:278517)

Expression

In Mice Carrying this Mutation:	96 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zcwpw1 Mutation: 32 strains or lines available

References

• Original: J:278517 Li M, et al., The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice. Sci Adv. 2019;5(8):eaax1101
• All: 1 reference(s)