Trim14^em1Rfw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim14^em1Rfw
• Name: tripartite motif-containing 14; endonuclease-mediated mutation 1, Rong-Fu Wang
• MGI ID: MGI:6358730
• Gene: Trim14 Location: Chr4:46505072-46536148 bp, - strand Genetic Position: Chr4, 24.84 cM, cytoband B2
• Alliance: Trim14^em1Rfw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• A CRISPR/Cas9 system was used to generate null alelle. (J:249057)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim14 Mutation: 24 strains or lines available

References

• Original: J:249057 Chen M, et al., TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses. Mol Cell. 2016 Oct 6;64(1):105-119
• All: 3 reference(s)