Tg(Lefty1-cre/ERT2)8Hmd
Transgene Detail

Summary

• Symbol: Tg(Lefty1-cre/ERT2)8Hmd
• Name: transgene insertion 8, Hiroshi Hamada
• MGI ID: MGI:6358748
• Synonyms: Lefty1(CreER^T2)
• Transgene: Tg(Lefty1-cre/ERT2)8Hmd Location: unknown
• Alliance: Tg(Lefty1-cre/ERT2)8Hmd page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Lefty1-cre/ERT2)8Hmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lefty1 (MGI:107405)

• Mutation details: The first exon of the mouse Lefty1 gene was replaced with cre/ERT2 sequence in BAC clone RP23-390I1 to produce a transgene. (J:278515)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lefty1 (mouse) Summary of all recombinase alleles driven by Lefty1. Comparative matrix view of recombinase activities Alliance mouse Lefty1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:278515 Takaoka K, et al., Origin and role of distal visceral endoderm, a group of cells that determines anterior-posterior polarity of the mouse embryo. Nat Cell Biol. 2011 May 29;13(7):743-52
• All: 2 reference(s)