Cela1^em1Rjv
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cela1^em1Rjv
• Name: chymotrypsin-like elastase family, member 1; endonuclease-mediated mutation 1, Rajiv L Joshi
• MGI ID: MGI:6359441
• Gene: Cela1 Location: Chr15:100572303-100585801 bp, - strand Genetic Position: Chr15, 56.38 cM, cytoband F1-F3
• Alliance: Cela1^em1Rjv page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting deleted portions of exon 2 and exon 7 to produced a knock-out allele. (J:278574)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cela1 Mutation: 29 strains or lines available

References

• Original: J:278574 Joshi R, et al., Role for Cela1 in Postnatal Lung Remodeling and Alpha-1 Antitrypsin-Deficient Emphysema. Am J Respir Cell Mol Biol. 2018 Aug;59(2):167-178
• All: 1 reference(s)