Abi3bp^tm1.1Smoc
Targeted Allele Detail

Summary

• Symbol: Abi3bp^tm1.1Smoc
• Name: ABI family member 3 binding protein; targeted mutation 1.1, Shanghai Model Organisms Center
• MGI ID: MGI:6359786
• Gene: Abi3bp Location: Chr16:56298241-56510498 bp, + strand Genetic Position: Chr16, 34.09 cM
• Alliance: Abi3bp^tm1.1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278622
• Parent Cell Line: PRX-129S6 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 4. An additional loxP site was inserted downsteam of exon 4. Cre-mediated recombination removed exon 4. Western blot analysis confirmed the absence of protein expression in lung homogenates. (J:278622)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abi3bp Mutation: 73 strains or lines available

References

• Original: J:278622 Yang H, et al., Knockout of Abi3bp in mice does not affect their olfactory function, mental state and NNK-induced lung tumorigenesis. Acta Biochim Biophys Sin (Shanghai). 2016 Sep;48(9):820-6
• All: 1 reference(s)